TFIIF is considered to be a general transcription factor

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AA change: V23A
¹ of Case:1/ Alive
Desease type:
squamous cell
neoplasms

AA change: R44Q
¹ of Case:1/ Alive
Desease type:
squamous cell
neoplasms

AA change: R51M
¹ of Case:1/ Alive
Desease type:
adenomas and
adenocarcinomas

AA change: T52P
¹ of Case:1/ Dead
Desease type: cystic,
mucinous and
serous neoplasm

AA change: G90E
¹ of Case:1/ Dead
Desease type:
squamous cell
neoplasms

AA change: S99I
¹ of Case:1/ Alive
Desease type:
adenomas and
adenocarcinomas

AA change: D102G
¹ of Case:1/ -
Desease type: cystic,
mucinous and
serous neoplasm

AA change: L104P
¹ of Case:1/ Alive
Desease type:
adenomas and
adenocarcinomas

Symbol: GTF2F2
Name: general transcription factor IIF, polypeptide 2, 30kDa
Synonyms: BTF4
_______________RAP30
_______________TFIIF

This substitution is one of the most significant affinity increase of the dimer among the others.

This substitution is one of the most significant affinity increase of the dimer among the others

TFIIF,2

TFIIF,1

Symbol:GTF2F1
Name: general transcription factor IIF, polypeptide 1, 74kDa
Synonyms:BTF4
______________RAP74
______________TF2F1
______________TFIIF

AA change: T122M
№ of Case:1/ 1
Desease type: thymic epithelial
neoplasms, adenomas and
adenocarcinomas

AA change: R151Q
№ of Case:1/1
Desease type: adenomas and adenocarcinomas

AA change: E158K
№ of Case:1/ 1
Desease type:
squamous cell
neoplasms

This substitution is one of the most significant affinity increase of the dimer among the others.

TFIIF,1

TFIIF,2